Pubertal timing and tempo differentially influence cortical and subcortical maturation in adolescence.

ABSTRACT: Puberty is a developmental period marked by an influx of sex steroids, which trigger physical and psychological changes. Furthermore, puberty elicits changes in structural brain development that are distinct from those associated with chronological age. Emerging evidence suggests that interindividual differences in pubertal development, such as timing, whether one reaches puberty milestones before or after peers, and tempo, or whether one progresses through puberty at a slower or faster rate than peers, may also play a significant role in shaping structural brain development. The present study leverages longitudinal data from the Adolescent Brain Cognitive Development^SM(ABCD Study®) to disentangle the influences of pubertal timing and tempo from chronological age on cortical and

SUBMITTER: McCann CF 

PROVIDER: S-EPMC12767848 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature