Vasoactive drug use in children with community acquired septic shock in Australia and New Zealand.

ABSTRACT:

Background

Vasoactive agents are a critical supportive therapy for children with sepsis. We describe the choice and use patterns of vasoactive agents in children with sepsis.

Methods

Prospective observational study conducted in 11 hospitals in Australia and New Zealand through the Paediatric Research in Emergency Departments International Collaborative (PREDICT) Network from April 2021 to December 2023. Children aged 0-<18 years with suspected sepsis were included. Children admitted to hospital and treated with parenteral antibiotics and either 1) a provisional diagnosis of sepsis, and/or 2) treatment for suspected sepsis (fluid bolus to treat poor perfusion). The frequency and sequence of use of vasoactive agents, and contributors to the choice of initial vasoactive were co

SUBMITTER: Long E 

PROVIDER: S-EPMC12767868 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature