Do hypoechoic endometrial cystic appearances before embryo transfer affect pregnancy rates in frozen-thawed cycles?

ABSTRACT:

Background

The presence of hypoechoic cystic lesions (HCL) within the endometrium has been proposed as a potential factor influencing implantation and pregnancy outcomes during frozen-thawed embryo transfer (FET) cycles. However, evidence regarding their clinical significance remains limited and inconsistent. This study aimed to evaluate the effect of endometrial HCLs detected by transvaginal sonography on pregnancy and live-birth outcomes in women undergoing FET.

Materials and methods

This retrospective study included 88 women undergoing hormone replacement therapy-FET cycles, divided into two groups: patients with HCLs (n = 44) and controls with a normal trilaminar endometrial pattern (n = 44). The primary outcome was the live birth rate (LBR), which represents the most cl

SUBMITTER: Karaosmanoglu O 

PROVIDER: S-EPMC12768274 | biostudies-literature | 2026

REPOSITORIES: biostudies-literature