Demonstration and technoeconomic analysis of dodecanol production from acetate using metabolically engineered Escherichia coli.

ABSTRACT: In a circular bioeconomy, the one-way conversion of petroleum to chemicals and CO₂ is replaced with processes that reduce CO₂ to energy carriers and useful materials that are returned to CO₂ upon combustion. A circular bioeconomy that relies on photosynthesis to generate sugars as the chief energy carrier and precursor to chemical building blocks has yet to overcome many recalcitrant aspects of plant-based photosynthesis, namely, high feedstock costs, arable land scarcity, food competition, and fertilizer overuse. Acetate is a potential sustainable energy carrier because it can be produced from CO₂ either electrocatalytically or by acetogens via the Wood-Ljungdahl pathway. In this work, we conducted a metabolic engineering study of Escherichia co

SUBMITTER: Perkovich PM 

PROVIDER: S-EPMC12768388 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature