Prognostic implications of N-terminal pro-B-type natriuretic peptide in patients undergoing transcatheter aortic valve implantation.

ABSTRACT:

Aims

N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a recognized marker of myocardial wall stress, but its prognostic role in patients undergoing transcatheter aortic valve implantation (TAVI) remains incompletely defined. This study assessed whether NT-proBNP levels at admission and discharge - interpreted using age-specific guideline thresholds - are associated with long-term clinical outcomes post-TAVI.

Methods and results

We retrospectively analysed 683 consecutive patients who underwent successful TAVI at Magna Graecia University between 2009 and 2023. NT-proBNP was measured at both admission and discharge. Patients were stratified into low or high NT-proBNP groups based on age-adjusted cutoffs. Among 468 patients with paired measurements, four NT-proBNP traje

SUBMITTER: Salerno N 

PROVIDER: S-EPMC12768887 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature