Association between FDG accumulation in interstitial lesions and acute exacerbation risk in lung cancer: multicenter analysis.

ABSTRACT:

Purpose

Interstitial pneumonia (IP) is associated with poor prognosis in lung cancer and increases the risk of acute exacerbation (AE). Few studies analyzed the relationship between fluorodeoxyglucose (FDG) accumulation in IP with lung cancer complicated with IP and the incidence of AE. This study investigates the association between FDG accumulation in the interstitial lesions and the AE incidence in patients with lung cancer complicated with IP.

Materials and methods

This multicenter, retrospective study included patients with lung cancer complicated with IP who received chemotherapy. All CTs at baseline and the onset of AE were centrally adjudicated. The SUVpeak and FDGscore for interstitial lesions were calculated from FDG positron emission tomography images before chemo

SUBMITTER: Ishida Y 

PROVIDER: S-EPMC12769495 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature