Association between anosognosia and neuropsychiatric symptoms in Alzheimer's disease dementia patients.

ABSTRACT: Anosognosia, the lack of awareness of memory decline, and Neuropsychiatric Symptoms (NPS) are prevalent and debilitating symptoms in Alzheimer's disease (AD) dementia. Understanding the coexistence of these symptoms may help guide clinical interventions and treatment strategies. This study aimed to compare NPS prevalence in patients with and without anosognosia at baseline and to assess the association between anosognosia and NPS over time. We examined patients with AD dementia enrolled in the Alzheimer's Disease Neuroimaging Initiative (ADNI). To be included in the current study, patients had to have undergone baseline assessments and at least one subsequent follow-up evaluation. Furthermore, all patients had to have amyloid (as assessed using Positron Emission Tomography, PET), Mini-Ment

SUBMITTER: Elnemais Fawzy M 

PROVIDER: S-EPMC12769538 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature