Epidemiology and control of hepatitis C virus infection in Brunei Darussalam: a retrospective cohort study.

ABSTRACT:

Objectives

We describe the epidemiology of hepatitis C virus (HCV) cases in Brunei Darussalam and evaluate factors associated with its treatment outcomes.

Methods

A retrospective cohort study was conducted using data from two national databases between January 2013 and December 2022.

Results

We identified 801 anti-HCV-positive cases. Although incidence remained relatively stable, prevalence rates increased from 10.1 to 48.7 per 100,00 population. Among those with detectable HCV RNA, treatment was initiated in 52.3% (n = 239). Locals (adjusted odds ratio [aOR] = 2.42, 95% confidence interval [CI] 1.16, 5.36) and age (30-39 years [aOR = 2.41, 95% CI 1.17, 5.07], 40-44 years [aOR = 2.55, 95% CI 1.19, 5.58], and 50-54 years [aOR = 2.76, 95% CI 1.25, 6.24) were associated

SUBMITTER: Koh KS 

PROVIDER: S-EPMC12769816 | biostudies-literature | 2026 Mar

REPOSITORIES: biostudies-literature