A Bayesian Modeling Framework for Health Care Resource Use and Costs in Trial-Based Economic Evaluations.

ABSTRACT: Individual-level data are routinely used in trial-based economic evaluations to assess the effectiveness and costs of a given intervention. While effectiveness measures are often expressed via utility scores derived from health-related quality-of-life instruments (e.g., EQ-5D questionnaires), information on different types of health care resource use (HRU) measures (e.g., number and types of services) are collected to compute the costs. Partially complete HRU data, particularly for self-reported questionnaires, are handled via ad hoc methods that rely on some assumptions (fill in a zero) that are typically hard to justify. Although methods have been proposed to account for the uncertainty surrounding missing data, particularly in the form of multiple imputation or Bayesian methods, these h

SUBMITTER: Gabrio A 

PROVIDER: S-EPMC12769925 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature