Mapping functional homologies between human and marmoset brain networks using movie-driven ultra-high field fMRI.

ABSTRACT: Naturalistic stimuli, such as movies, offer a powerful tool for probing functional brain organization across species. Using movie-driven functional magnetic resonance imaging (md-fMRI), we recorded brain activity in humans and awake marmosets exposed to the same dynamic audiovisual stimulus. We applied tensor independent component analysis (tICA) to identify functional networks in each species, hierarchically cluster them, and examine their within- and between-species temporal correlations to assess functional homologies. We found strong interspecies correspondence in core sensory networks, particularly those involved in visual and auditory processing, suggesting conserved mechanisms for sensory integration. In contrast, networks associated with higher-order cognition, including prefrontal

SUBMITTER: Zanini A 

PROVIDER: S-EPMC12770604 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature