CtDNA to Predict Treatment Response in Head and Neck Squamous Cell Carcinoma: A Systematic Review.

ABSTRACT:

Objective

To investigate the potential role of plasma circulating tumor DNA (ctDNA) in predicting treatment response in HPV-positive and HPV-negative Head and Neck Squamous Cell Carcinoma (HNSCC).

Data sources

Medline, PubMed, Cochrane databases (Cochrane Library, Cochrane Central Register of Controlled Trials) and EMBASE databases were searched in accordance with the standard PICOTS model.

Review methods

Search results were independently reviewed by two primary authors. Disagreements were adjudicated by the senior author. Studies were excluded according to defined exclusion criteria. Studies were assessed for quality in accordance with the REMARK guidelines. Data were then extracted, and findings were discussed narratively.

Results

From a total of 1026 article

SUBMITTER: Jones O 

PROVIDER: S-EPMC12770799 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature