Impact of deceased donor acute kidney injury (AKI) on renal transplant outcomes.

ABSTRACT:

Aims

Donor AKI is a common reason for discarding deceased donor kidneys due to uncertainty regarding transplant outcomes. Our study investigated the effect of AKI in donor kidneys on post-transplantation outcomes.

Methods

Medline, Embase, Cochrane and Web of Science were searched. Risk of bias assessment was performed. 2984 studies were identified by the search, 34 met the inclusion criteria. A total of 103,529 kidney transplants were analysed, 97,165 (94 %) with and 6364 (6 %) without donor AKI.

Results

There was no significant difference between recipients of grafts from donors with terminal serum creatinine >2.0 mg/dl and < 2.0 mg/dl in 1 year serum creatinine (MD: -0.01, CI: -0.09-0.07, P = 0.84), 1 year patient survival (RR: 0.99, CI: 0.96-1.02, P =

SUBMITTER: Nozdrin M 

PROVIDER: S-EPMC12771102 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature