Prevalence of cognitive frailty, reversible and potentially reversible cognitive frailty among older adults without dementia: a systematic review and meta-analysis.

ABSTRACT:

Objectives

Cognitive frailty (CF) is characterized by the coexistence of physical frailty and cognitive impairment, while potentially reversible cognitive frailty (PRCF) and reversible cognitive frailty (RCF) refer to two related conditions that may be modifiable or responsive to interventions. This study aimed to estimate the pooled prevalence of CF, PRCF, and RCF among older adults without dementia.

Methods

A search of six literature databases was conducted from inception to August 15, 2024. Cohort and cross-sectional studies reporting CF, PRCF, or RCF prevalence in older adults aged 60+ without dementia were included. Random-effects meta-analyses with logit-transformed prevalence were performed, along with subgroup analyses and meta-regression.

Results

Of the 13,10

SUBMITTER: Bian J 

PROVIDER: S-EPMC12771507 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature