How physical activity influences motoric cognitive risk syndrome in older adults.

ABSTRACT:

Objective

Motoric cognitive risk (MCR) is a pre-dementia syndrome linked to higher risks of cognitive decline and dementia. This study aims to investigate the relationship between total physical activity (TPA), healthy physical activity (PA), and MCR in older adults.

Study design

Population-based cohort study with both cross-sectional and longitudinal analyses.

Methods

Logistic regression was used for cross-sectional analyses to examine the associations between TPA, healthy PA, and MCR at baseline. Using mediation analysis to explore the associations of gait speed and cognition in the link between physical activity and MCR. Cox regression was applied for longitudinal analyses to evaluate the relationships between TPA, healthy PA, and incident MCR risk over a 5-year fo

SUBMITTER: Chen X 

PROVIDER: S-EPMC12771774 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature