Prenatal-postnatal integrated management model improves outcomes of neonatal cardiac surgery in critical congenital heart disease: a retrospective cohort study.

ABSTRACT:

Background

Neonates with CCHD remain at high risk for mortality. This study aimed to evaluate the impact of the prenatal-postnatal integrated management model (PPIMM) on perioperative outcomes and mortality in neonates with CCHD, and to identify factors associated with mortality.

Methods

This retrospective cohort study enrolled 274 neonates with CCHD undergoing cardiac surgery from January 2018 to August 2024. Patients were categorized into the PPIMM group (n = 140) and the non-PPIMM group (n = 134). The primary outcome was all-cause mortality, including operative mortality and late mortality. The secondary outcome was unplanned reoperation. Kaplan-Meier survival and Cox regression analyses were performed.

Results

The PPIMM group underwent surgery at a younger age (8.

SUBMITTER: Sun Y 

PROVIDER: S-EPMC12771998 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature