Postural changes in retinal vascular parameters and risk of diabetic retinopathy progression in type 2 diabetes mellitus: a pilot study.

ABSTRACT:

Background

To investigate whether postural changes in retinal vascular parameters, measured using smartphone-based imaging, differ between healthy individuals and patients with diabetes mellitus (DM), and whether these changes independently predict diabetic retinopathy (DR) progression over a 5-year period.

Methods

Retinal images were captured using a smartphone with a clip-on adapter lens in sitting and supine positions. Vascular parameters (caliber, fractal dimension, tortuosity, branching) were quantified using the Singapore I Vessel Assessment software. Cross-sectional analyses compared postural-induced vascular responses between 38 healthy controls and 49 DM participants. DM participants were followed for 5 years, with DR progression defined as ≥ 2-step increase in seve

SUBMITTER: Nguyen TX 

PROVIDER: S-EPMC12772113 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature