Peripheral blood inflammatory cytokines linked to clinical outcomes in <i>Mycoplasma pneumoniae</i> pneumonia.

ABSTRACT: Mycoplasma pneumoniae pneumonia (MPP) can result in a variety of poor prognoses. A retrospective cohort study of MPP patients admitted to the Children's Hospital of Nanjing Medical University from 1 January 2021 to 1 April 2024 was carried out to evaluate the association between 12 peripheral blood inflammatory cytokines and clinical outcomes. 2,391 patients were enrolled and divided into four outcome-based groups: severe MPP (SMPP), refractory MPP (RMPP), necrotizing pneumonia (NP), and pulmonary embolism (PE). The levels of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-10 (IL-10), and interleukin-17 were elevated in the poor-prognosis groups of SMPP and RMPP. Interferon-γ (IFN-γ) was upregulated in the poor-prognosis groups of RMPP, and it was an influencing factor for t

SUBMITTER: Bao Y 

PROVIDER: S-EPMC12772330 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature