Advanced imaging of corneal neovascularisation with a novel swept-source AS-OCTA system.

ABSTRACT:

Aims

To explore the clinical application of a novel swept-source anterior segment optical coherence tomography angiography (AS-OCTA) system for imaging corneal neovascularisation (CoNV), assessing limbal vasculature and detecting short-term vascular changes following pharmacologic vasoconstriction.

Methods

This cross-sectional observational study included 20 eyes: 10 with clinically diagnosed CoNV of various aetiologies and 10 healthy controls. Each eye underwent AS-OCTA imaging using the BMizar 400kHz Full-Range Swept-Source OCT system at baseline and after administration of 10% phenylephrine (PE). FlowArea (mm²) was automatically calculated across predefined circular regions of interest (ROIs) encompassing the cornea, limbus and episclera. In corneal and limbal

SUBMITTER: Lucchino L 

PROVIDER: S-EPMC12772550 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature