Nocturnal gastro-oesophageal reflux and pulmonary abnormalities on chest CT in a general population: the Swedish CArdioPulmonary BioImage Study.

ABSTRACT:

Background

Nocturnal gastro-oesophageal reflux (nGER) is common in people with respiratory diseases, but its association with pulmonary abnormalities is not known.

Aim

Investigate the association between nGER and pulmonary abnormalities on chest CT in an adult general population.

Methods

In total, 28 846 individuals from the general population aged 50-64 years completed questionnaires and underwent chest CT, in the Swedish CArdioPulmonary BioImage Study (www.scapis.org). Participants with nGER symptoms on ≥1 night per week were defined as having nGER. Chest CT was evaluated for bronchial wall thickening, bronchiectasis, reticular abnormalities, honeycombing, cysts and ground glass opacities. Ever-smoking, current asthma, inflammatory bowel disease and autoimmune disea

SUBMITTER: Emilsson OI 

PROVIDER: S-EPMC12772615 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature