Longitudinal modelling of growth in neonates exposed to antenatal steroids to quantify associations with final height: a cohort study.

ABSTRACT:

Objective

To assess the associations of antenatal steroids with child growth.

Design

Longitudinal observational cohort study started in 1994.

Setting

A single tertiary neonatal centre in Sheffield, UK.

Participants

Of 254 individuals recruited, two were excluded, 48 born at term; 202 (57% boys, 87% white ethnicity) modelled had a median of 19 height measurements each (Q1:12 to Q3:21) up to median age 15.8 years (Q1:9.9 to Q3:16.9).

Interventions

Data on administration of antenatal steroids were collected alongside gestational age and parental height.

Main outcome measures

Height was modelled with SuperImposition by Translation and Rotation (SITAR) to extract each person's peak velocity and age at peak velocity via the SITAR random effects of 'size

SUBMITTER: Lawrence NR 

PROVIDER: S-EPMC12772621 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature