An Ultra-Brief Informant Questionnaire for Case Finding of Cognitive Impairment Across Diverse Literacy: Diagnostic Accuracy Study.

ABSTRACT:

Background

Undiagnosed cognitive impairment poses a global challenge, prompting recent interest in ultra-brief screening questionnaires (comprising <2 to 3 items) to efficiently identify individuals needing further evaluation. However, evidence on ultra-brief questionnaires remains limited, particularly regarding their validity across diverse literacy levels.

Objective

This study aimed to develop an ultra-brief questionnaire that performs well in detecting mild cognitive impairment or dementia (MCI/dementia) across diverse literacy levels and to compare its performance with an established questionnaire (the 8-item Informant Interview to Differentiate Aging and Dementia [AD8]).

Methods

This diagnostic study involved 1856 participants aged ≥65 years (median education 10

SUBMITTER: Liew TM 

PROVIDER: S-EPMC12772941 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature