Antagonistic regulation of nitrogen and drought signaling mediated by NIN-like protein 7 transcription factor in <i>Arabidopsis thaliana</i>.

ABSTRACT: Plants face the constant challenge of reconciling antagonistic environmental signals, such as nutrient-driven growth and water deficit-induced stress responses. However, the molecular mechanisms that integrate these conflicting pathways remain poorly understood. Through a comprehensive transcriptomic meta-analysis in Arabidopsis thaliana, we show that nitrogen (N) supply and water deficit signaling exhibit overlapping and often opposing gene expression responses. Regulatory network modeling identifies the NIN-LIKE PROTEIN 7 (NLP7) transcription factor (TF) as a central integrator of these convergent transcriptional responses. Through combinatorial water deficit and N supply treatments in wild-type and nlp7 mutant plants, we find that NLP7 accounts for 85% of the transcription

SUBMITTER: Johnson NR 

PROVIDER: S-EPMC12773779 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature