Effectiveness of a reactive oral cholera vaccination during a cholera outbreak at the Douala New-Bell Central Prison in Cameroon.

ABSTRACT:

Background

Research on cholera vaccine effectiveness in prison populations is scarce, despite evidence of OCV benefits in general outbreak settings. During a major cholera outbreak in Douala's overcrowded central prison, Cameroon deployed the Euvichol oral cholera vaccine. This study assessed the vaccine's association with reduced cholera-related hospitalisation among inmates.

Methods

A retrospective secondary data analysis was conducted in 2024 on inmates who were targeted for reactive vaccination during a cholera outbreak in 2022. A stratified sampling strategy based on gender and housing type was used to select eligible inmates. Vaccine status was ascertained from the prison's vaccination register. Our outcome variable of interest was cholera-related hospitalisation. Logi

SUBMITTER: Bekolo CE 

PROVIDER: S-EPMC12774372 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature