Red Cell Distribution Width is Associated with Bleeding Complications after Coronary Artery Bypass Grafting.

ABSTRACT:

Objectives

Elevated red cell distribution width (RDW) has been associated with adverse outcomes in coronary artery disease but its role in bleeding after cardiac surgery is unclear. We evaluated whether preoperative RDW predicts bleeding after isolated coronary artery bypass grafting (CABG).

Methods

This was a nationwide retrospective study of patients undergoing isolated CABG in Iceland, 2003-2019. RDW was analysed continuously (per 1% increase) and dichotomized (>14.0% vs ≤14.0%). Primary bleeding outcomes included transfusion >4 red blood cell units, re-exploration for bleeding, and chest tube output >1000 mL/24h. Multivariable logistic regression adjusted for demographics, comorbidities, operative urgency, cardiopulmonary bypass, and perioperative factors.

Results

SUBMITTER: Heimisdottir AA 

PROVIDER: S-EPMC12774467 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature