The angiosome and woundosome concepts in guiding revascularization for chronic limb-threatening ischemia and diabetic foot ulcers-a narrative review.

ABSTRACT:

Background and objective

The angiosome concept, introduced by Taylor et al. and further applied by Neville et al., divides the body into three-dimensional blocks of tissue supplied by specific source arteries. This anatomical framework has been instrumental in guiding targeted revascularization strategies, thus enhancing blood flow to ischemic wounds. Building upon this, the woundosome concept was recently introduced, which focuses on individualized perfusion targeting, based on (I) anatomic variations; (II) the presence and extent of collateral circulation; and (III) wound characteristics. The woundosome concept may offer a potentially more tailored approach, paving the way for more thoughtful tissue revascularization. This review aims to investigate the role of angi

SUBMITTER: Moysidis T 

PROVIDER: S-EPMC12775154 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature