Anatomic-sex interaction effects and prognostic stratification in mucoepidermoid carcinoma of the oral cavity minor salivary glands.

ABSTRACT:

Background

To investigate the impact of anatomic-sex interaction effects on survival outcomes in mucoepidermoid carcinoma (MEC) of the oral cavity minor salivary glands.

Methods

A retrospective cohort study utilizing the Surveillance, Epidemiology, and End Results (SEER) database (2000-2021) analyzed 923 MEC cases. Cases were stratified into four anatomic subsites: Palate, Lateral_oral, Palate_other, and Other_oral. Kaplan-Meier survival analysis, standardized residual testing via chi-square tests, and multivariable Cox proportional hazards models were employed to assess anatomic-sex interactions. A risk-stratified follow-up protocol was proposed.

Results

The 5- and 10-year overall survival (OS) rates were 94.7% and 92.6%, respectively. 1. Significant OS differences a

SUBMITTER: Zheng H 

PROVIDER: S-EPMC12775234 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature