Renal sarcomas in children and adolescents: a retrospective, multicenter cohort study.

ABSTRACT:

Background

Renal sarcomas arise rarely in children and adolescents and represent a histologically and biologically diverse disease category. Consequently, standardizing optimal therapies for pediatric renal sarcomas remains challenging. Leveraging a large North American research collaborative, the purposes of this study were to evaluate the current state of patient, disease, and survival characteristics among pediatric renal sarcomas and to expose knowledge gaps that will inform future discovery.

Methods

Patients 21 years or younger and treated for a primary renal sarcoma between January 1st, 2000 and November 30th, 2022 were identified through the Pediatric Surgical Oncology Research Collaborative. Patient (e.g., demographics) and disease (e.g., histology, stage, molecular

SUBMITTER: McKay KG 

PROVIDER: S-EPMC12775861 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature