Development of magnetic COFs for simultaneous extraction and determination of aflatoxin B1 and benzo(a)pyrene.

ABSTRACT: Aflatoxin B1 (AFB1) and benzo(a)pyrene (B(a)P) are representative co-occurring contaminants at trace levels in food samples. However, their simultaneous extraction and detection remain challenging due to differing polarities, low concentrations, and matrix interferences. Herein, a hydroxyl-functionalized imine-linked magnetic covalent organic framework (Fe₃O₄@COFs-DhaTab) was synthesized via a one-pot, room-temperature condensation. Fe₃O₄@COFs-DhaTab enabled a one-sorbent, one-workflow extraction of AFB1 and B(a)P via synergistic π-π stacking and hydrogen bonding. Fe₃O₄@COFs-DhaTab exhibited equilibrium adsorption capacities of 3.64 and 8.23 mg/g for AFB1 and B(a)P, respectively. Coupled with high-performance liquid chromato

SUBMITTER: Wang S 

PROVIDER: S-EPMC12775938 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature