SNX24 serves as a potential prognostic biomarker and a therapeutic target in uterine corpus endometrial carcinoma according to bioinformatics and experimentations.

ABSTRACT:

Background

Uterine corpus endometrial carcinoma (UCEC) which is originated from endometrial epithelium, ranks the second among frequent malignant tumors in female reproductive system. The discovery of novel therapeutic targets is urgently needed to address unmet clinical demands. In this study, we conducted a comprehensive bioinformatic analysis to identify key drivers of UCEC.

Methods

The prognostic factors for UCEC were analyzed by Human Protein Atlas (HPA), The University of ALabama at Birmingham CANcer data analysis Portal (UALCAN), and Encyclopedia of RNA Interactomes (ENCORI). The expression levels of the overlapped prognostic factors were analyzed by UALCAN, and ENCORI. The heatmap of the potential 12 prognostic factors was exhibited by UALCAN. The online databases in

SUBMITTER: Long D 

PROVIDER: S-EPMC12776183 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature