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CSF diversion after aneurysmal sub-arachnoid hemorrhage: towards personalized treatment strategies.


ABSTRACT: Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition associated with high morbidity and mortality, with survivors often experiencing long-term neurological and functional deficits. Cerebrospinal fluid (CSF) diversion plays a pivotal role in the acute management of aSAH, both for the treatment of hydrocephalus and for the prevention of delayed cerebral ischemia (DCI) through clearance of blood breakdown products. Four principal modalities are currently employed: lumbar puncture, lumbar, cisternal, and external ventricular drain. Each technique differs in its mechanism of drainage, monitoring capacity, complication profile, and influence on shunt dependency and long-term outcome. High-quality evidence from randomized controlled trials now supports lumbar drainage as the

SUBMITTER: Klug J 

PROVIDER: S-EPMC12777169 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature