Biochanin A improves nitrogen utilization efficiency by regulating ruminal microbial community in dairy goats.

ABSTRACT:

Background

Rumen microbial nitrogen metabolism is crucial for animal health, productivity, and environmental sustainability in ruminants. Natural products like biochanin A are garnering interest as potential feed additives due to their beneficial effects and safety profiles. Here, we collected total mixed diet, plasma, milk, urine, and feces samples of dairy goats to evaluate the impact of biochanin A on nitrogen metabolism and elucidated regulatory mechanisms of nitrogen metabolism using multi-omics approaches by analyzing plasma metabolites and ruminal microbial communities.

Results

Supplementation with biochanin A significantly enhanced nitrogen utilization efficiency of dairy goats. Plasma metabolomics revealed that biochanin A altered pathways related to amino acid bios

SUBMITTER: Zhang X 

PROVIDER: S-EPMC12777280 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature