Cryotherapy in joint arthroplasty rehabilitation: Effects on pain, analgesic consumption, blood loss, and range of motion.

ABSTRACT:

Background

Effectiveness of cryotherapy in the rehabilitation of joint arthroplasty remains controversial. Our systematic review was to evaluate application of cryotherapy following total joint arthroplasty on outcome measures related to rehabilitation exercise.

Methods

PubMed, Web of Science, Cochrane Library, Embase, and CIHAHL, Grey literature, and other relevant databases for randomized controlled trials were searched. A meta-analysis was performed using Revman5.3, and we used Cochrane risk-of-bias 2.0 (RoB2.0) tool to evaluated the quality of included literature. We also use GRADEprofiler 3.6 software for evidence quality assessment.

Results

A systematic review of 21 studies, with a pooled analysis of 1462 patients (1177 total knee arthroplasty [TKA] and 285 tota

SUBMITTER: Xie Y 

PROVIDER: S-EPMC12778110 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature