Tumour control, eye retention and visual acuity after radiotherapy for choroidal melanoma.

ABSTRACT:

Objective

Radiotherapy modalities such as iodine-125 (I¹²⁵) and ruthenium-106 (Ru¹⁰⁶) brachytherapy and proton beam radiotherapy (PBR) are well established for the treatment of choroidal melanoma. This study aimed to evaluate the rates of local tumour control, globe retention and visual acuity (VA) outcomes in patients with choroidal melanoma treated with I¹²⁵ or Ru¹⁰⁶ brachytherapy or PBR.

Methods and analysis

A review was conducted of all cases of choroidal melanoma treated with Ru¹⁰⁶ or I¹²⁵ brachytherapy or PBR over a 10-year period. Patient demographics, comorbidities, tumour characteristics, treatment parameters and VA outcomes were analysed. A predictive nomogram was developed to estimate final VA based

SUBMITTER: Murtagh P 

PROVIDER: S-EPMC12778298 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature