Previous tuberculosis modifies spirometry outcomes among small-scale gemstone miners in Tanzania: a cross-sectional, clinic-based study.

ABSTRACT:

Introduction

Small-scale miners are known to experience high silica exposures, associated with high rates of silicosis and Tuberculosis (TB). TB has been shown to worsen underlying impairment of lung function in miners. We describe the spirometry outcomes, according to previous TB status, among a large cohort of small-scale miners attending a screening centre.

Methods

We collected cross-sectional spirometry and clinical data from consecutive miners and ex-miners, with negative Xpert TB results, attending a screening clinic in Northern Tanzania, between February 2018 and December 2020. Spirometry values assessed using the ATS/ERS 2019 quality criteria and compared with GLI 2022 global (GLIgl) reference values. We used multiple linear regression to model excess Forced Expirato

SUBMITTER: Mtei FJ 

PROVIDER: S-EPMC12778310 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature