Thrombectomy Use in the United States for Basilar Artery Occlusion in the Era of Neutral Clinical Trials: 2018 to 2020 Analysis of the National Inpatient Sample.

ABSTRACT:

Background

In 2019 and 2020, 2 randomized trials of basilar artery occlusion (BAO) thrombectomy reported no improvement in functional outcomes with thrombectomy, despite observational evidence. The objective of this study was to assess whether neutral clinical trials may have influenced BAO thrombectomy practice.

Methods

The National Inpatient Sample (2018-2020) was queried for US patients with BAO, and comparisons were made between patients admitted in 2020 versus 2018 to 2019 for the primary outcome of thrombectomy. Unadjusted and adjusted multivariable regression was used, accounting for demographic and clinical covariates, with propensity-score matching to balance clinical and hospital-level characteristics between years.

Results

Of the 14 945 patients with BAO, 3

SUBMITTER: Siegler JE 

PROVIDER: S-EPMC12778452 | biostudies-literature | 2024 Jan

REPOSITORIES: biostudies-literature