Blood Pressure Management Following Endovascular Stroke Treatment: A Feasibility Trial and Meta-Analysis of Outcomes.

ABSTRACT:

Background

Although postprocedure blood pressure (BP) correlates with outcome in patients undergoing endovascular thrombectomy (EVT), the optimal target is unknown.

Methods

We performed a pilot randomized-controlled clinical trial enrolling participants with persistently elevated BP after successful EVT. Participants were randomized within 1 hour from the end of EVT to either intensive (systolic BP target <140 mmHg) or standard BP target (systolic BP <180 mmHg) for 48 hours. The main end point was feasibility, which was assessed with the enrollment rate and adherence to allocated BP target. Exploratory end points included neurologic deterioration, functional improvement, intracranial hemorrhage, and flow dynamics detected by transcranial Doppler ultrasonography. We included

SUBMITTER: Katsanos AH 

PROVIDER: S-EPMC12778499 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature