Prevalence of Systemic Hypertension and the Effects of Cerebral Revascularization in Patients With Moyamoya Disease.

ABSTRACT:

Background

Hypertension is often codiagnosed in patients with moyamoya disease (MMD), a progressive intracranial steno-occlusive vasculopathy; this has principally been attributed to renal artery stenosis (up to 10%). Susceptibility MMD genes, including ring finger protein 213/mysterin and GUCY1A3, have also been linked to extracranial vascular disease and increased systolic blood pressure. We aimed to define the prevalence of systemic hypertension in MMD patients and characterize its evolution after cerebral revascularization.

Methods

Patients with MMD treated with extracranial-intracranial bypass from 2014 to 2018 were retrospectively enrolled. Blood pressure measurements and antihypertensive agent use were recorded pre- and postoperatively. Hypertension was defined

SUBMITTER: Lee H 

PROVIDER: S-EPMC12778507 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature