Endovascular Thrombectomy With and Without Preceding Thrombolysis in Posterior Circulation Stroke-Insights From STAR.

ABSTRACT:

Background

Multiple randomized trials could not establish the noninferiority of endovascular thrombectomy (EVT) alone without preceding intravenous thrombolysis (IVT) or superiority of IVT followed by EVT in anterior circulation large-vessel occlusion stroke. The role of prior IVT in posterior circulation large-vessel occlusion remains controversial.

Methods

In this multicenter, retrospective study, patients with stroke with large-vessel occlusion in the posterior circulation who received EVT alone or with IVT were selected from the stroke thrombectomy and aneurysm registry between 2013 and 2022. Effects of IVT followed by thrombectomy on favorable functional outcome (defined as modified Rankin scale≤3 at 90 days) and safety were investigated using multivariable logistic and

SUBMITTER: Heide EC 

PROVIDER: S-EPMC12778559 | biostudies-literature | 2024 Sep

REPOSITORIES: biostudies-literature