Trends in Thrombolysis and Thrombectomy Use in Patients With Ischemic Stroke and Cancer.

ABSTRACT:

Background

To determine how intravenous thrombolysis (IV-tPA) and mechanical thrombectomy (MT) use has changed in patients with acute ischemic stroke (AIS) with cancer (AIS-C) compared with patients with AIS and noncancer (AIS-NC) in the United States since publication of pivotal MT trials.

Methods

All primary AIS-NC and AIS-C admissions (weighted N=5 748 357) were identified from the 2007 to 2019 Nationwide Inpatient Sample. Joinpoint and multivariable-adjusted models with interaction terms were used to compare the rate of change in IV-tPA and MT use between AIS-C and AIS-NC.

Results

From 2007 to 2019, 4.4% of AIS admissions had active cancer. Overall IV-tPA use in AIS-C (6.4%) was lower than that of AIS-NC (8.5%) (P<0.001) but use differed by cancer subtype (

SUBMITTER: Otite FO 

PROVIDER: S-EPMC12778595 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature