A Decade of Improvement in Door-to-Puncture Times for Mechanical Thrombectomy But Ongoing Stagnation in Prehospital Care.

ABSTRACT:

Background

Systems of care surrounding endovascular therapy for stroke have garnered much attention in recent years. In-hospital metrics, such as "door-to-puncture" and procedure times have been areas for quality improvement. The temporal trend and clinical significance of prehospital "onset-to-door" time, however, remains unknown.

Methods

We performed a systematic review of time metric data from all published randomized controlled and investigational device exemption trials involving endovascular therapy for stroke between 2005 and 2019 (n=26). Second, we conducted a record-level observational analysis on a total of 3512 patients from 3 real-world registries (Mechanical Embolus Removal in Cerebral Ischemia [MERCI], Thrombectomy REvascularization of Large Vessel Occlusions i

SUBMITTER: Sun CH 

PROVIDER: S-EPMC12778601 | biostudies-literature | 2023 Jan

REPOSITORIES: biostudies-literature