Leptomeningeal Collateral Status by Signal Variance in Perfusion Magnetic Resonance Imaging: Association With Initial Stroke Severity and Early Functional Outcome After Thrombectomy.

ABSTRACT:

Background

Collaterals are the main determinants of the severity of cerebral ischemia and control the pace of the ischemic tissue damage in acute ischemic stroke. Assessment of collateral status remains a major challenge in stroke imaging. We evaluated a signal variance-based collateral vessel index in perfusion-weighted imaging (CVI_PWI) in terms of its association with initial stroke severity, presence of a mismatch for endovascular thrombectomy (EVT), and early functional outcome in patients with large-vessel occlusion.

Methods

T2*-weighted time series from dynamic susceptibility contrast perfusion imaging were processed to calculate the CVI_PWI. Ischemic cores were segmented automatically on apparent diffusion coefficient maps. The relationship betwee

SUBMITTER: Helwig N 

PROVIDER: S-EPMC12778668 | biostudies-literature | 2023 Jul

REPOSITORIES: biostudies-literature