External Validation of Atherosclerotic Neuroimaging Biomarkers in Emergent Large-Vessel Occlusion.

ABSTRACT:

Background

Intracranial atherosclerosis related large vessel occlusion (ICAS-LVO) is the major cause of failed mechanical thrombectomy. ICAS-LVO causes reocclusion or a fixed focal stenosis, leading to suboptimal revascularization and poor functional outcomes. We aimed to externally validate 4 preidentified imaging biomarkers of ICAS-LVO: absent hyperdense sign, Hounsfield units (Hu ratio ≤1.1 and Delta Hu <6) and truncal-type occlusion, observed on admission noncontrast computed tomography and computed tomography angiography in patients presenting with emergent large-vessel occlusion (ELVO).

Methods

We conducted a retrospective cohort observational study of consecutive patients presenting with acute M1/terminal internal carotid artery occlusions undergoing mechanical thromb

SUBMITTER: Siddiqui FM 

PROVIDER: S-EPMC12778695 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature