Association of Time Course of Thrombectomy and Outcomes for Large Acute Ischemic Region: RESCUE-Japan LIMIT Subanalysis.

ABSTRACT:

Background

The effectiveness of endovascular thrombectomy (EVT) has been proven even in patients with large cerebral infarction in the early time window. However, the association of the time course with the treatment effect is unknown. The aim of this analysis was to evaluate the influence of the time course from stroke onset to reperfusion on the therapeutic effect of EVT.

Methods

The subjects were patients with occlusion of large vessels and sizable strokes on imaging (Alberta Stroke Program Early Computed Tomographic score 3-5) in RESCUE-Japan LIMIT (Recovery by Endovascular Salvage for Cerebral Ultra-Acute Embolism-Japan Large Ischemic Core Trial), a multicenter, randomized, clinical open-label trial of EVT versus medical care alone. In the current analysis, the clinical

SUBMITTER: Ishihara H 

PROVIDER: S-EPMC12778703 | biostudies-literature | 2023 Sep

REPOSITORIES: biostudies-literature