Nationwide Trends in Reperfusion Therapy and Outcomes of Acute Ischemic Stroke According to Severity: The Japan Stroke Data Bank.

ABSTRACT:

Background

It is unclear whether all patient subgroups with acute ischemic stroke have benefited from advances in reperfusion therapy. We investigated long-term trends of reperfusion therapy and outcomes according to the stroke severity.

Methods

Patients with acute ischemic stroke registered in the prospective nationwide hospital-based registry between 2000 and 2020 were examined. Baseline National Institutes of Health Stroke Scale (NIHSS) score ≥10 and ≤5 was considered to indicate possible large vessel occlusions and minor deficits, respectively. Secular changes were assessed per 5-year cohorts (2000-2005, 2006-2010, 2011-2015, 2016-2020). Outcomes included favorable outcome (modified Rankin scale score 0-2 at discharge).

Results

Of 127 741 patients, NIHSS score was

SUBMITTER: Koge J 

PROVIDER: S-EPMC12778722 | biostudies-literature | 2023 Nov

REPOSITORIES: biostudies-literature