Exploring the Unmet Need in Acute Ischemic Stroke Patients Not Treated With Intravenous Alteplase: The Get With The Guidelines-Stroke Registry.

ABSTRACT:

Background

Early administration of intravenous tissue plasminogen activator (IV alteplase) improves functional outcomes in patients with acute ischemic stroke, yet many patients are not treated with IV alteplase. There is a need to understand the reasons for nontreatment and the short- and long-term outcomes in this patient population.

Methods

We analyzed patients ≥65 years old with a primary diagnosis of acute ischemic stroke presenting within 24 hours of time last known well (LKW) but not treated with IV alteplase from 1630 Get With The Guidelines-Stroke hospitals in the United States between January 2016 and December 2016. We report clinical characteristics, reasons for withholding treatment, in-hospital mortality, and 90-day and 1-year outcomes including costs, stratifie

SUBMITTER: Mac Grory B 

PROVIDER: S-EPMC12778747 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature