Endovascular Therapy Versus Medical Therapy Alone for Basilar Artery Stroke: A Systematic Review and Meta-Analysis Through Nested Knowledge.

ABSTRACT:

Background

Endovascular thrombectomy (EVT) is an effective treatment for acute ischemic stroke attributable to the anterior circulation large-vessel occlusion. Randomized trials of patients with posterior circulation large-vessel occlusion (PC-LVO) have failed to show a benefit of EVT over medical therapy (MEDT). We performed a systematic review and meta-analysis to understand better whether EVT is beneficial for PC-LVO.

Methods

Using the Nested Knowledge AutoLit living review platform, we identified randomized control trials and prospective studies that reported functional outcomes in patients with PC-LVO treated with EVT versus MEDT. The primary outcome variable was 90-day modified Rankin scale score of 0 to 3, and secondary outcome variables included 90-day modified Ranki

SUBMITTER: Adusumilli G 

PROVIDER: S-EPMC12778767 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature