Stroke Severity and Early Ischemic Changes Predict Infarct Growth Rate and Clinical Outcomes in Patients With Large-Vessel Occlusion.

ABSTRACT:

Background

The infarct growth rate (IGR) measures ischemic stroke progression and varies among patients. Clinicoradiological phenotypes of IGR are poorly understood. We evaluated the association of presentation stroke severity and early ischemic changes with infarct progression in patients who underwent successful thrombectomy.

Methods

This is a retrospective cohort observational study of consecutive endovascular therapy patients with anterior circulation large-vessel occlusion strokes and successful reperfusion (modified Thrombolysis in Cerebral Ischemia≥2b) from 2 comprehensive stroke centers. National Institutes of Health Stroke Scale and Alberta Stroke Program Early CT [Computed Tomography] Score (ASPECTS) were scored at admission. IGR was defined as the final infarct vo

SUBMITTER: Quispe-Orozco D 

PROVIDER: S-EPMC12778790 | biostudies-literature | 2022 Jul

REPOSITORIES: biostudies-literature