Impact of the <i>RNF213</i> p.R4810K Variant on Endovascular Therapy for Large-Vessel Occlusion Stroke.

ABSTRACT:

Background

We investigated the impact of the ring finger protein 213 p.R4810K variant, a founder variant for moyamoya disease in East Asians, on endovascular therapy outcomes in patients with acute anterior-circulation large-vessel occlusion stroke in comparison with noncarriers.

Methods

Of the consecutive patients with ischemic stroke admitted to our institute from 2011 to 2021, patients who underwent endovascular therapy for acute occlusion of the intracranial internal carotid artery or M1 segment of the middle cerebral artery were included. Outcomes were instant reocclusion, final modified Thrombolysis in Cerebral Infarction reperfusion ≥2b, and early reocclusion. Instant reocclusion was defined as the occurrence of reocclusion during the procedure, and early reocclusion

SUBMITTER: Yoshimoto T 

PROVIDER: S-EPMC12778837 | biostudies-literature | 2022 Nov

REPOSITORIES: biostudies-literature