Transcutaneous Retrobulbar Amphotericin B Injection Treatment for Invasive Fungal Rhino-Orbital Sinusitis: A Case Report.

ABSTRACT:

Introduction

Invasive fungal rhino-orbital sinusitis is a rare and life-threatening condition that occurs in immunosuppressed patients. This article aimed to describe the case of a patient with bilateral orbital mucormycosis treated with right orbital exenteration and transcutaneous retrobulbar amphotericin B (AMPB) in the left orbit.

Case presentation

A 61-year-old diabetic woman, immunosuppressed due to treatment with immunotherapy for breast cancer and systemic corticosteroid for sarcoidosis, was admitted to our hospital with complaints of severe headache, fever, and complete right visual loss. Imaging exams demonstrated an invasive pansinusitis with right orbital apex involvement, extension to frontal cerebral space and an inflammatory swelling in the medial aspect of th

SUBMITTER: Ferreira AM 

PROVIDER: S-EPMC12779292 | biostudies-literature | 2026 Jan-Dec

REPOSITORIES: biostudies-literature