Seizures in pediatric thyroid storm: Two cases and a literature review.

ABSTRACT: Thyroid storm is a life-threatening disorder caused by thyrotoxicosis. Diagnostic criteria in adults emphasize central nervous system (CNS) symptoms, including seizures, as CNS symptoms are associated with irreversible damage. However, children have a lower seizure threshold than adults, which may lead to overestimation of severity in pediatric cases with seizures. This study reports two pediatric cases of thyroid storm with seizures, fever, and tachycardia. The more severe case remained unconscious and restless, necessitating intubation and intensive care. The other case regained consciousness spontaneously following the initiation of treatment for thyroid storm. A literature review of 84 children and adolescents with thyroid storm revealed 16 cases (19%) that exhibited seizures. The prev

SUBMITTER: Kawashima S 

PROVIDER: S-EPMC12779379 | biostudies-literature | 2026 Jan

REPOSITORIES: biostudies-literature